Iron Man (1968) #24
"My Son, the Minotaur!" is written by Archie Goodwin and drawn by Johnny Craig and George Tuska. If you were wondering what happened to the tragic Madame Masque after the dramatic events of issue #19, wonder no more. Cast ashore on a lonely Mediterranean island, the woman with the golden face wakes to see a bull-headed man looming over her. The nightmare ends abruptly as she is smashed against a rock wall by the man-beast. But when she wakens, Madame Masque is in the company of Dr. Vyrolak, a plastic surgeon who claims he can restore her beauty.
Many months pass and with no word of whether Madame Masque (a.k.a. Whitney Frost) has lived or died, S.H.I.E.L.D. agent Jasper Sitwell struggles to come to grips with his feelings. Having seen Whitney and Tony Stark together before her disappearance, does Jasper seek her out to reclaim her love or to gain his revenge for her betrayal? When both the lovesick agent and Iron Man track Madame Masque down, they find her soon to become even more misshapen. Dr. Vyrolak, rather than curing the former Maggia leader, seeks to make her like his own son–a bull-headed Minotaur and thereby begin a race of superior animal-men that he can control!